製品紹介
ホタテ由来プラズマローゲンに関する研究論文をまとめています。
- 論文
- 学会発表
| 2025 | Plasmalogen-Containing Scallop-Derived Lipids Affect the Endocrine System of Caenorhabditis elegans Nematodes and Improved Its Lifespan and Health Riku Inoue, Kazuichi Sakamoto Food and Nutrition Sciences. 2025 June; 16(6): 729-740 |
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| 2025 | Plasmalogen as a Bioactive Lipid Drug: From Preclinical Research Challenges to Opportunities in Nanomedicine Wu Y, Deng Y, Angelov B, Angelova A. FASEB Bioadv. 2025 Jun 4;7(8):e70028. doi: 10.1096/fba.2025-00010. eCollection 2025 Aug. |
| 2024 | Lipid and Transcriptional Regulation in a Parkinson's Disease Mouse Model by Intranasal Vesicular and Hexosomal Plasmalogen-Based Nanomedicines Wu Y, Wang J, Deng Y, Angelov B, Fujino T, Hossain MS, Angelova A. Adv Healthc Mater. 2024 Jun;13(14):e2304588. doi: 10.1002/adhm.202304588. Epub 2024 Feb 28. |
| 2024 | Protective effect of scallop-derived plasmalogen against vascular dysfunction, via the pSTAT3/PIM1/NFATc1 axis, in a novel mouse model of Alzheimer's disease with cerebral hypoperfusion Zhai Y, Morihara R, Feng T, Hu X, Fukui Y, Bian Z, Bian Y, Yu H, Sun H, Takemoto M, Nakano Y, Yunoki T, Tang Y, Ishiura H, Yamashita T. Brain Res. 2024 Apr 1;1828:148790. doi: 10.1016/j.brainres.2024.148790. Epub 2024 Jan 23. |
| 2024 | Comparison of Daiwa Brain Health (Hokkaido Scallop Oil Plasmalogen) and Prevagen (Apoaequorin) on Cognitive Function: An In-Office Pilot Study Pescatore F. Altern Ther Health Med. 2024 Oct;30(10):18-20. |
| 2023 | The Effects of HSOP on Cognition, Depression, and Activities of Daily Living in Older Adults with Cognitive Issues John E. Lewis, Lonnie A. Fravel TOWNSEND LETTER The Examiner of Alternative Medicine. 2023 March 29. |
| 2023 | The Effects of HSOP on Cognition, Depression, and Activities of Daily Living in Older Adults with Cognitive Issues Lewis JE, Fravel LA. Intefrative Medicine, Vol.21, No.6, January 2023, 16-20 |
| 2022 | The Effect of HSOP (Hokkaido Scallop Oil Plasmalogen) on POMS2 Test Score Naoki Igari, Kentaro Ninomiya, Hideki Katano TOWNSEND LETTER – FEBRUARY/MARCH 2022; 60, 62-63. |
| 2022 | Orally Administered Plasmalogens Alleviate Negative Mood States and Enhance Mental Concentration: A Randomized, Double-Blind, Placebo-Controlled Trial Fujino M, Fukuda J, Isogai H, Ogaki T, Mawatari S, Takaki A, Wakana C, Fujino T. Front Cell Dev Biol. 2022 Jun 2;10:894734. doi: 10.3389/fcell.2022.894734. eCollection 2022. |
| 2022 | Clinical and Pathological Benefits of Scallop-Derived Plasmalogen in a Novel Mouse Model of Alzheimer's Disease with Chronic Cerebral Hypoperfusion Feng T, Hu X, Fukui Y, Bian Z, Bian Y, Sun H, Takemoto M, Yunoki T, Nakano Y, Morihara R, Abe K, Yamashita T. J Alzheimers Dis. 2022;86(4):1973-1982. doi: 10.3233/JAD-215246. |
| 2022 | Ethanolamine plasmalogens derived from scallops stimulate both follicle-stimulating hormone and luteinizing hormone secretion by bovine gonadotrophs Hiroya Kadokawa, Miyako Kotaniguchi, Shiro Mawatari, Risa Saito, Takehiko Fujino, Shinichi Kitamura Sci Rep. 2022 Oct 6;12(1):16789. doi: 10.1038/s41598-022-20794-4. |
| 2022 | Plasmalogens, the vinyl ether-linked glycerophospholipids, enhance learning and memory by regulating brain-derived neurotrophic factor Huang C, Zhang F, Xu Z, Wei J. Sensors (Basel). 2022 Feb 21;22(4):1678. doi: 10.3390/s22041678. |
| 2022 | The Effects of HSOP on Cognition, Depression, and Activities of Daily Living in Older Adults with Cognitive Issues John E Lewis, Lonnie A Fravel Integr Med (Encinitas). 2022 Dec;21(6):16–20. |
| 2021 | Neuroprotective effects of Scallop-derived plasmalogen in a mouse model of ischemic stroke Feng T, Hu X, Fukui Y, Tadokoro K, Bian Z, Morihara R, Yamashita T, Abe K. Brain Res. 2021 Sep 1;1766:147516. doi: 10.1016/j.brainres.2021.147516. Epub 2021 May 12. |
| 2020 | Therapeutic Efficacy of Plasmalogens for Alzheimer's Disease, Mild Cognitive Impairment, and Parkinson's Disease in Conjunction with a New Hypothesis for the Etiology of Alzheimer's Disease Fujino T, Hossain MS, Mawatari S. Adv Exp Med Biol. 2020;1299:195-212. doi: 10.1007/978-3-030-60204-8_14. |
| 2020 | Improvement of blood plasmalogens and clinical symptoms in Parkinson's disease by oral administration of ether phospholipids: A preliminary report Mawatari S, Ohara S, Taniwaki Y, Tsuboi Y, Maruyama T, Fujino T. Parkinsons Dis. 2020 Feb 19;2020:2671070. doi: 10.1155/2020/2671070. eCollection 2020. |
| 2019 | Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells Ali F, Hossain MS, Sejimo S, Akashi K. Mol Neurobiol. 2019 May;56(5):3404-3419. doi: 10.1007/s12035-018-1307-2. Epub 2018 Aug 20. |
| 2019 | Plasmalogens and Alzheimer's disease: a review Su XQ, Wang J, Sinclair AJ. Lipids Health Dis. 2019 Apr 16;18(1):100. doi: 10.1186/s12944-019-1044-1. |
| 2018 | Effects of Plasmalogen on Patients with Mild Cognitive Impairment (MCI) Takehiko Fujino, Tatsuo Yamada, Takashi Asada, Midori Ichimaru, Yoshio Tsuboi, Chikako Wakana, Shiro Mawatari J Alzheimers Dis Parkinsonism 2018, Vol 8(1): 419. doi: 10.4172/2161-0460.1000419 |
| 2017 | Efficacy and blood plasmalogen changes by oral administration of plasmalogen in patients with mild Alzheimer's disease and mild cognitive impairment: a multicenter, randomized, double-blind, placebo-controlled trial Fujino T, Yamada T, Asada T, Tsuboi Y, Wakana C, Mawatari S, Kono S. EBioMedicine. 2017 Mar;17:199-205. doi: 10.1016/j.ebiom.2017.02.012. Epub 2017 Feb 24. |
| 2004 | Fatty acids of serine, ethanolamine, and choline plasmalogens in some marine bivalves Kraffe E, Soudant P, Marty Y. Lipids. 2004 Jan;39(1):59-66. doi: 10.1007/s11745-004-1202-x. |