A new scientific paper titled “Protective Effects of Biobran/MGN-3 Against Etoposide-Induced Immune Modulation and Hepatotoxicity in Male Rats” has been published by a research group led by Ali M. Eldib of Damanhur University, Egypt.

Etoposide is a widely used chemotherapeutic drug that may cause adverse effects such as liver toxicity, oxidative stress, and immune dysfunction. In this preclinical study, researchers investigated BioBran/MGN-3 in male rats treated with etoposide. The study evaluated liver function and histological changes, oxidative stress and antioxidant markers, and immune and inflammatory parameters associated with etoposide treatment.

Journal: Journal of Applied Pharmaceutical Science. 2025;15(10):100–113.
Authors: Ali M. Eldib, Heba E. Mostafa, Rania E. Mufti, Zayed M. Alnefaie, Osman Suliman, Amr Eldardear, Faris M. Elmahdi, Ibrahim H. Babikir, Sara M. Altom, Mohamed S. El-Gerbed, Mamdooh H. Ghoneum, Sarah A. Almohammadi, Nafisah M. Alshamry, Asma O. Elkhalifa, Ibtihal N. Albalwai, Modhi A. Saleem, Heba S. Khalifa, Attalla F. El-kott, Hytham M. Abdelatif.