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2025.12.24 Society

New Research Publication: Study of BioBran in Human iPS Cell–Derived Neuronal Networks

A new scientific paper on BioBran has been published by a research group led by Dr. Basant K. Puri of Cambridge Advanced Research. The paper is titled “Modulation of Glutamatergic Burst Activity by Hydrolysed Arabinoxylan Rice Bran: A Multielectrode Array Study in Human-Induced Pluripotent Stem Cell-Derived Neurones and Astrocytes”.

In this in vitro study, researchers investigated hydrolysed arabinoxylan rice bran (BioBran) using neuronal networks composed of human-induced pluripotent stem cell (iPSC)-derived neurones and astrocytes. Using multielectrode array (MEA) recordings, the study evaluated neuronal network activity, with a particular focus on glutamatergic burst activity under conditions of neural excitation.

Journal: Cureus. 2025;17(1):e77694.
Authors: Basant K. Puri, Cecilia Catuogno-Cal, Ivan Verduci

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