A collaborative research team from Mansoura University, the National Research Centre, and Pharos University in Egypt, as well as Charles R. Drew University of Medicine and Science in the United States, has published a study on BioBran, titled “Protective Effect of Biobran/MGN-3, an Arabinoxylan from Rice Bran, Against the Cytotoxic Effects of Polyethylene Nanoplastics in Normal Mouse Hepatocytes: An In Vitro and In Silico Study.”

The study investigated BioBran/MGN-3, a rice bran-derived arabinoxylan, in normal mouse hepatocytes exposed to polyethylene nanoplastics. Using both in vitro experiments and computational (in silico) approaches, the researchers evaluated cellular responses associated with nanoplastic-induced cytotoxicity and investigated the molecular interactions and pathways involved.

Journal: Nutrients. 2025, 17(12), 1993
Authors: Heba Allah M. Elbaghdady, Rasha M. Allam, Mahmoud I. M. Darwish, Maha O. Hammad, Hewida H. Fadel and Mamdooh H. Ghoneum.