(1) NKCP Actions
Reduced risk of thrombus formation requires: 1) clot formation prevention 2) maintenance of normal blood viscosity and 3) lysing blood clots (thrombi).
NKCP, derived from Bacillus subtilis natto, has been shown to perform these three functions.
(2) Supporting Scientific Data
１) Anticoagulant effect
①Anticoagulant effect of NKCP in human blood（簡・繁）
②Anticoagulant effect of NKCP in a rat model of thrombus formation（簡・繁）
2) Action of preventing increase in blood viscosity
Effect of NKCP on the viscosity of human blood（簡・繁）
3) Thrombolytic effect
①Thrombolytic effect of NKCP on artificial thrombi（簡・繁）
②In vivo thrombolytic effect of oral NKCP in experimental thrombolysis
model （簡・繁）
③Identification of proteases derived from Bacillus subtilis natto related
to thrombolysis（簡・繁）
(3) Clinical Study Results
Effect of Bacillus subtilis natto derived protein on the human blood
coagulation/ fibrinolysis system（簡・繁）
